SCHEMBL4452207

SCHEMBL4452207

CS(=O)(=O)Nc1cc(S(=O)(=O)O)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 5/20 0.66
GNB1 P62873 5/20 0.66
PHLPP2 Q6ZVD8 2/20 0.62
P2RY4 P51582 8/20 0.60
CYP1A2 P05177 2/20 0.59
CYP2C9 P11712 2/20 0.59
ALOX15 P16050 2/20 0.59
HSD17B10 Q99714 2/20 0.59
ALDH1A1 P00352 1/20 0.59
CYP3A4 P08684 1/20 0.59
HPGD P15428 1/20 0.59
MAPK1 P28482 1/20 0.59
CYP2C19 P33261 1/20 0.59
HIF1A Q16665 1/20 0.59
CDK2 P24941 3/20 0.55
PGAM1 P18669 1/20 0.52
P2RY2 P41231 7/20 0.51
P2RY12 Q9H244 6/20 0.51
P2RY6 Q15077 4/20 0.51
P2RY1 P47900 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11651457 0.86 GNG2 (0.77) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL11612508 0.85 GNG2 (0.64) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL11348178 0.85 GNG2 (0.75) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL7534351 0.84 GNG2 (0.63) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL20333857 0.84 GNG2 (0.66) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL9174847 0.84 CDK2 (0.79) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL31037859 0.84 CDK2 (0.79) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL7538903 0.83 CDK2 (0.77) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL11343919 0.83 GNG2 (0.65) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL10611340 0.83 GNG2 (0.65) GNG2GNB1PHLPP2P2RY4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090249564-A1 HAIR DYE COMPOSITIONS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2009-10-08 US disclosed
CN-101379145-A Hair dyeing composition DYSTAR TEXTILFARBEN GMBH & CO (DE) 2009-03-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090249564-A1 HAIR DYE COMPOSITIONS TYR, CDY1; CDY1B, ZYX GNG2 1636/4885GNB1 1466/4885PHLPP2 2813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.