⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154645 | 0.77 | — | — | |
| SCHEMBL24073187 | 0.74 | ALDH1A1 (0.37) | — | |
| SCHEMBL8813456 | 0.73 | — | — | |
| SCHEMBL576905 | 0.71 | — | — | |
| SCHEMBL12158575 | 0.71 | MGAM (0.53) | — | |
| Ethylene SCHEMBL21749883 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL1052875 | 0.71 | — | — | |
| SCHEMBL11426169 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL1766405 | 0.69 | — | — | |
| Bicarbonate SCHEMBL16592510 | 0.69 | SMN1; SMN2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629494-B2 | Process for producing cyclopropylphenol derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20090054681-A1 | Production Process of cyclopropylphenol derivatives | SANKYO AGRO COMPANY, LIMITED (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1880987-A1 | PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE | Sankyo Agro Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| CN-1125817-C | Quinazoline derivatives as VEGF inhibitors | ZENECA LTD (GB) | 2003-10-29 | — | — | CN | disclosed |
| CN-1211239-A | Quinazoline derivatives as VEGF inhibitors | ZENECA LTD (GB) | 1999-03-17 | — | — | CN | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |