Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | THPO | P40225 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylcysteine SCHEMBL4448262 | 0.97 | KDM4E (0.72) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL5422065 | 0.97 | KDM4E (0.72) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL9133375 | 0.94 | KDM4E (0.68) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL1069666 | 0.93 | KDM4E (0.78) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL28429060 | 0.93 | KDM4E (0.78) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL7934239 | 0.93 | KDM4E (0.78) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL14775437 | 0.93 | KDM4E (0.78) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL5905824 | 0.92 | KDM4E (0.75) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL4404186 | 0.92 | KDM4E (0.75) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL4404187 | 0.92 | KDM4E (0.75) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190240169-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS UTILIZING A D-AMINO ACID | AAS, LLC (US) | 2019-08-08 | — | — | US | disclosed |
| US-10265278-B2 | Pharmaceutical compositions and methods utilizing a D-amino acid | AMINO ACID SOLUTIONS, INC. | 2019-04-23 | — | — | US | disclosed |
| US-20170157066-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS UTILIZING A D-AMINO ACID | AAS, LLC (US) | 2017-06-08 | — | — | US | disclosed |
| EP-2249822-B1 | PHARMACEUTICAL COMPOSITIONS AND METHODS UTILIZING A D-AMINO ACID AND AN ANTIOXIDANT FOR TREATING NEUROPSYCHIATRIC DISORDERS | AMINO ACID SOLUTIONS INC (US) | 2016-01-06 | — | — | EP | disclosed |
| US-20090176715-A1 | Pharmaceutical Compositions and Methods Utilizing a D-Amino Acid | AMINO ACIDS SOLUTIONS INC. (US) | 2009-07-09 | — | — | US | disclosed |