Acetylcysteine

Acetylcysteine

SCHEMBL7934239

CC(=O)NC(CS)C(=O)O.NC(CS)C(=O)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.78
MAPT P10636 1/20 0.78
THRB P10828 1/20 0.78
ALOX15 P16050 1/20 0.78
NFKB1 P19838 1/20 0.78
PTGS2 P35354 1/20 0.78
THPO P40225 1/20 0.78
RECQL P46063 1/20 0.78
BLM P54132 1/20 0.78
SMN1; SMN2 Q16637 1/20 0.78
PTGS1 P23219 2/20 0.59
SLC7A11 Q9UPY5 1/20 0.59
ACE P12821 1/20 0.50
ALDH1A1 P00352 1/20 0.48
FOLH1 Q04609 1/20 0.43
GSTK1 Q9Y2Q3 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
GNPAT O15228 1/20 0.39
FNTA P49354 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetylcysteine SCHEMBL1069666 1.00 KDM4E (0.78) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL28429060 1.00 KDM4E (0.78) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL14775437 1.00 KDM4E (0.78) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL5905824 0.98 KDM4E (0.75) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL28158658 0.98 KDM4E (0.75) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL4404186 0.98 KDM4E (0.75) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL4404187 0.98 KDM4E (0.75) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL9133375 0.93 KDM4E (0.68) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL4452370 0.93 KDM4E (0.68) KDM4EMAPTTHRBALOX15NFKB1
Cysteine SCHEMBL23539583 0.89 NFKB1 (0.61) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111315414-A Methods of producing drug-loaded polymer scaffolds and protein-polymer-drug conjugates 梅尔莎纳医疗公司 2020-06-19 CN disclosed
CN-109198648-A Golden worm cancer liberator base enzyme peptide 苟春虎 2019-01-15 CN disclosed
CN-108112809-A Improve the preparation method of the rabbit feed of rabbit hair glossiness 浦江县协盈动物饲料技术开发有限公司 2018-06-05 CN disclosed
CN-1356981-A Pharmaceutical compounds NICOX SA (FR) 2002-07-03 CN disclosed
US-6239301-B1 USING A CYSTEINE DERIVATIVE ZAMBON GROUP S.P.A. (IT) 2001-05-29 US disclosed