⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538238 | 0.70 | — | — | |
| SCHEMBL23722482 | 0.67 | ALDH1A1 (0.47) | — | |
| SCHEMBL2201872 | 0.67 | — | — | |
| SCHEMBL1454612 | 0.67 | — | — | |
| SCHEMBL1721841 | 0.67 | — | — | |
| SCHEMBL38146 | 0.67 | — | — | |
| Water SCHEMBL11631396 | 0.67 | — | — | |
| SCHEMBL403230 | 0.64 | — | — | |
| SCHEMBL2944033 | 0.64 | — | — | |
| SCHEMBL10445858 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629494-B2 | Process for producing cyclopropylphenol derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20090054681-A1 | Production Process of cyclopropylphenol derivatives | SANKYO AGRO COMPANY, LIMITED (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1880987-A1 | PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE | Sankyo Agro Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| US-5597931-A | Total synthesis of taxol and analogues thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1996034862-A1 | TOTAL SYNTHESIS OF TAXOL AND ANALOGUES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-11-07 | — | — | WO | disclosed |
| US-5527924-A | ANTICARCINOGENIC AGENTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-06-18 | — | — | US | disclosed |
| US-5488116-A | Total synthesis of taxol and analogues thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-01-30 | — | — | US | disclosed |
| US-5416225-A | Chemical intermediates | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1995-05-16 | — | — | US | disclosed |
| WO-1995012567-A1 | TOTAL SYNTHESIS OF TAXOL AND ANALOGUES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1995-05-11 | — | — | WO | disclosed |
| WO-1993020036-A1 | TOTAL SYNTHESIS OF TAXOL | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-10-14 | — | — | WO | disclosed |
| US-4880814-A | 7-cycloalkyl naphthyridines | ABBOTT LABORATORIES (US) | 1989-11-14 | — | — | US | disclosed |
| US-4233296-A | STEROIDS HAVING PROGESTOMIMETIC PROPERTIES | ROUSSEL UCLAF (FR) | 1980-11-11 | — | — | US | disclosed |
| EP-0007404-A1 | Synthesis of 2-hydroxy-2-acetyl-1,2,3,4-tetrahydronaphthalene compounds | THE UNIVERSITY OF KANSAS (US) | 1980-02-06 | — | — | EP | disclosed |