Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390233 | 0.89 | GPR119 (0.66) | GPR119CYP2C9 | |
| SCHEMBL389617 | 0.87 | GPR119 (0.73) | GPR119CYP2C9 | |
| SCHEMBL390039 | 0.83 | GPR119 (0.72) | GPR119CYP2C9 | |
| SCHEMBL386787 | 0.83 | GPR119 (0.80) | GPR119CYP2C9 | |
| SCHEMBL391379 | 0.82 | GPR119 (0.69) | GPR119CYP2C9 | |
| SCHEMBL1906298 | 0.82 | GPR119 (0.71) | GPR119CYP2C9 | |
| SCHEMBL389521 | 0.82 | GPR119 (0.73) | GPR119CYP2C9 | |
| SCHEMBL391698 | 0.82 | GPR119 (0.68) | GPR119CYP2C9 | |
| SCHEMBL389552 | 0.82 | GPR119 (0.75) | GPR119CYP2C9 | |
| SCHEMBL391292 | 0.81 | GPR119 (0.77) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808168-B1 | Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level | ARENA PHARM INC (US) | 2009-06-03 | — | — | EP | disclosed |