Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27370385 | 0.84 | LMNA (0.60) | PDPK1MAPTMEN1ALDH1A1LMNA | |
| SCHEMBL27964925 | 0.83 | JAK3 (0.53) | PDPK1KAT6AHDAC2CASRMAPT | |
| SCHEMBL20557647 | 0.81 | CNR1 (0.64) | MAPTMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL30469224 | 0.81 | CNR1 (0.64) | MAPTMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL15606528 | 0.81 | PDPK1 (0.58) | PDPK1KAT6APTGDR2CDK2CYP2A6 | |
| SCHEMBL4355764 | 0.78 | PDPK1 (0.55) | PDPK1KAT6APTGDR2NTRK1NPC1 | |
| SCHEMBL2654169 | 0.78 | PDPK1 (0.50) | PDPK1KAT6AHDAC2PTGDR2MAPT | |
| SCHEMBL939202 | 0.77 | KAT6A (0.60) | PDPK1KAT6AHDAC2PTGDR2FFAR1 | |
| SCHEMBL30850854 | 0.77 | KAT6A (0.60) | PDPK1KAT6AHDAC2PTGDR2FFAR1 | |
| SCHEMBL15805858 | 0.77 | PDPK1 (0.72) | PDPK1KAT6AHDAC2PTGDR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |