SCHEMBL4452738

SCHEMBL4452738

CC[P+](CC)(CC)CC.Cc1ccccc1S(=O)(=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.41
NPSR1 Q6W5P4 6/20 0.39
ALDH1A1 P00352 6/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
P2RY2 P41231 3/20 0.39
P2RY4 P51582 3/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
KMT2A Q03164 4/20 0.38
HSD11B1 P28845 1/20 0.36
MAPT P10636 5/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 3/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
NSD2 O96028 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4463635 0.84 MEN1 (0.42) RAPGEF4NPSR1ALDH1A1P2RY2P2RY4
SCHEMBL135009 0.84 HSD11B1 (0.42) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A
SCHEMBL20533883 0.84 HSD11B1 (0.42) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A
SCHEMBL6915057 0.84 HSD11B1 (0.42) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A
SCHEMBL5399285 0.84 HSD11B1 (0.42) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A
SCHEMBL57931 0.84 TDP1 (0.45) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A
SCHEMBL16034284 0.84 TDP1 (0.45) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A
SCHEMBL20658918 0.84 HSD11B1 (0.42) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A
SCHEMBL8954958 0.84 HSD11B1 (0.42) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A
SCHEMBL6915627 0.84 HSD11B1 (0.42) RAPGEF4ALDH1A1P2RY2P2RY4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7482333-B2 Blend of an aromatic polycarbonate, a silica filler, a phosphonium sulfonate, and a mono- or di-phosphate ester of a polyoxyalkylene alkyl or aryl ether; antistatic agents; improved impact strength, fluidity and handling performance without decreasing fire and heat resistances IDEMITSU KOSAN CO., LTD. (JP) 2009-01-27 US disclosed
US-20070213437-A1 Polycarbonate Resin Composition And Moldings Thereof IDEMITSU KOSAN CO., LTD (JP) 2007-09-13 US disclosed
EP-0953605-B1 Flow improved polycarbonate composition TEIJIN LTD (JP) 2004-09-15 EP disclosed
EP-0640646-B1 Process for production of stabilized polycarnonate TEIJIN LTD (JP) 2002-11-06 EP disclosed
EP-1221459-A1 A stabilized polycarbonate TEIJIN LIMITED (JP) 2002-07-10 EP disclosed
US-6103856-A LINEAR AROMATIC POLYCARBONATE WHICH HAS BEEN PREPARED BY REACTING AN AROMATIC DIHYDROXY COMPOUND WITH A CARBONATE PRECURSOR THROUGH SOLUTION OR MELT POLYCONDENSATION AND CYCLIC AROMATIC CARBONATE TEIJIN LIMITED (JP) 2000-08-15 US disclosed
EP-0953605-A2 Flow improved polycarbonate composition TEIJIN LIMITED (JP) 1999-11-03 EP disclosed
US-5668202-A ADDING ORGANOSULFONATE OR SULFATE STABILIZER AFTER MELT POLYCONDENSATION TEIJIN LIMITED (JP) 1997-09-16 US disclosed
US-5494952-A CATALYTIC MELT CONDENSATION OF AROMATIC DIHYDROXY COMPOUND AND A CARBONIC ACID DIESTER UNTIL DESIRED VISCOSITY IS REACHED, THEN MIXING WITH STABILIZER CONTAINING QUATERNARY AMMONIUM OR PHOSPHONIUM SALTS OF ORGANIC SULFONIC ACIDS TEIJIN LIMITED (JP) 1996-02-27 US disclosed
US-5486555-A Process for production of stabilized polycarbonate TEIJIN LIMITED (JP) 1996-01-23 US disclosed
EP-0640646-A1 Process for production of stabilized polycarnonate TEIJIN LIMITED (JP) 1995-03-01 EP disclosed