Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MDH2 | P40926 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30416773 | 1.00 | KDM4E (0.77) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL2818109 | 0.90 | KDM4E (0.66) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL30417250 | 0.90 | KDM4E (0.66) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL6620700 | 0.87 | KDM4E (1.00) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL18589525 | 0.82 | CYP1A2 (0.64) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL30906941 | 0.81 | F7 (0.66) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL12786892 | 0.81 | CYP1A2 (0.62) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL4537810 | 0.81 | CYP1A2 (0.62) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL2974546 | 0.81 | ALDH1A1 (0.62) | KDM4EHPGDCYP1A2ALDH1A1MEN1 | |
| SCHEMBL4342972 | 0.81 | CYP1A2 (0.62) | KDM4EHPGDCYP1A2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009040377-A2 | IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2009-04-02 | — | — | WO | claimed |
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |
| WO-2009040377-A2 | IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009040377-A2 | IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2009-04-02 | — | — | WO | disclosed |