SCHEMBL4452880

SCHEMBL4452880

CO[Si](CCCNCCNCCCNCCN)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.50
CA6 P23280 5/20 0.50
CA7 P43166 5/20 0.50
CA9 Q16790 5/20 0.50
CA14 Q9ULX7 5/20 0.50
CA5B Q9Y2D0 5/20 0.50
CA2 P00918 4/20 0.50
CA4 P22748 4/20 0.50
CA5A P35218 4/20 0.50
CA3 P07451 3/20 0.50
LMNA P02545 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
ALOX15 P16050 3/20 0.46
CA1 P00915 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
KDM4E B2RXH2 1/20 0.44
CASP2 P42575 2/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2799082 0.98 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL37873 0.98 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL1585330 0.98 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL28947390 0.98 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL29040171 0.98 CA12 (0.52) CA12CA6CA7CA9CA14
SCHEMBL4445789 0.98 CA12 (0.52) CA12CA6CA7CA9CA14
SCHEMBL16652321 0.96 CA12 (0.46) CA12CA6CA7CA9CA14
SCHEMBL5891867 0.96 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL5711364 0.96 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL19549 0.96 CA12 (0.48) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697150-B1 CROSSLINKABLE ELASTOMERIC COMPOSITION AND TIRE FOR VEHICLE WHEELS COMPRISING THE SAME PIRELLI & C SPA (IT) 2009-04-01 EP disclosed
US-20070185239-A1 Crosslinkable elastomeric composition and tire for vehicle wheels comprising the same PIRELLI & C. S.P.A. (IT) 2007-08-09 US disclosed
EP-1697150-A1 CROSSLINKABLE ELASTOMERIC COMPOSITION AND TIRE FOR VEHICLE WHEELS COMPRISING THE SAME Pirelli & C. S.p.A. (IT) 2006-09-06 EP disclosed
WO-2005058615-A1 CROSSLINKABLE ELASTOMERIC COMPOSITION AND TIRE FOR VEHICLE WHEELS COMPRISING THE SAME PIRELLI & C. S.P.A. (IT) 2005-06-30 WO disclosed
US-20040094252-A1 Process for manufacturing, moulding and curing tyres for vehicles wheels PIRELLI PNEUMATICI S.P.A. (IT) 2004-05-20 US disclosed
EP-1339539-A1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI PNEUMATICI Società per Azioni (IT) 2003-09-03 EP disclosed
WO-2002045942-A1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI PNEUMATICI S.P.A (IT) 2002-06-13 WO disclosed