SCHEMBL4445789

SCHEMBL4445789

CO[Si](CCCNCCCNCCN)(OC)OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.52
CA6 P23280 5/20 0.52
CA7 P43166 5/20 0.52
CA9 Q16790 5/20 0.52
CA14 Q9ULX7 5/20 0.52
CA5B Q9Y2D0 5/20 0.52
CA2 P00918 4/20 0.52
CA4 P22748 4/20 0.52
CA5A P35218 4/20 0.52
CA3 P07451 3/20 0.52
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
RECQL P46063 2/20 0.43
LMNA P02545 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
ALOX15 P16050 3/20 0.42
CA1 P00915 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29040171 1.00 CA12 (0.52) CA12CA6CA7CA9CA14
SCHEMBL4452880 0.98 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL19549 0.98 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL5711364 0.98 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL5891867 0.98 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL8669640 0.96 CA12 (0.46) CA12CA6CA7CA9CA14
Ammonia Solution, Strong SCHEMBL10482257 0.96 CA12 (0.46) CA12CA6CA7CA9CA14
Hydrochloric Acid SCHEMBL18686410 0.96 CA12 (0.46) CA12CA6CA7CA9CA14
Ammonia Solution, Strong SCHEMBL21530853 0.96 CA12 (0.46) CA12CA6CA7CA9CA14
Hydrochloric Acid SCHEMBL3935447 0.96 CA12 (0.46) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8029577-B2 Lightening and/or dyeing of human keratin fibres via a composition comprising a particular amino silicon compound and composition and device L'OREAL S.A. (FR) 2011-10-04 US disclosed
US-7909889-B2 Lightening and/or coloring human keratin fibers using at least one aminotrialkoxy silane or at least one aminotrialkenyloxy silane composition L'OREAL S.A. (FR) 2011-03-22 US disclosed
US-20100297049-A1 LIGHTENING AND/OR DYEING OF HUMAN KERATIN FIBRES BY MEANS OF A COMPOSITION COMPRISING A PARTICULAR AMINO SILICON COMPOUND AND COMPOSITION AND DEVICE L'OREAL S.A. (FR) 2010-11-25 US disclosed
US-20100275387-A1 LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION L'OREAL S.A. (FR) 2010-11-04 US disclosed
EP-1697150-B1 CROSSLINKABLE ELASTOMERIC COMPOSITION AND TIRE FOR VEHICLE WHEELS COMPRISING THE SAME PIRELLI & C SPA (IT) 2009-04-01 EP disclosed
US-20070185239-A1 Crosslinkable elastomeric composition and tire for vehicle wheels comprising the same PIRELLI & C. S.P.A. (IT) 2007-08-09 US disclosed
EP-1339539-B9 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI (IT) 2005-06-15 EP disclosed
EP-1339539-B1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI (IT) 2005-01-19 EP disclosed
US-20040094252-A1 Process for manufacturing, moulding and curing tyres for vehicles wheels PIRELLI PNEUMATICI S.P.A. (IT) 2004-05-20 US disclosed
EP-1339539-A1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI PNEUMATICI Società per Azioni (IT) 2003-09-03 EP disclosed
WO-2002045942-A1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI PNEUMATICI S.P.A (IT) 2002-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100275387-A1 LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION KRT18, FABP4, ALDH7A1 CA12 723/4885CA6 1264/4885CA7 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.