SCHEMBL4453090

SCHEMBL4453090

O=C(c1cccc2ccccc12)N1CC1

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.77
LMNA P02545 1/20 0.77
USP2 O75604 1/20 0.70
POLB P06746 1/20 0.68
HTT P42858 1/20 0.68
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
AVPR1A P37288 1/20 0.62
TGM2 P21980 2/20 0.62
KDM4E B2RXH2 1/20 0.59
HIF1A Q16665 1/20 0.59
NR4A1 P22736 1/20 0.57
NR4A2 P43354 1/20 0.57
NR4A3 Q92570 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3582934 0.93 ALDH1A1 (0.68) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL6430908 0.93 ALDH1A1 (0.68) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL3518475 0.92 ALDH1A1 (0.67) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL25247976 0.91 ALDH1A1 (0.66) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL14720666 0.91 ALDH1A1 (0.66) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL28570849 0.91 ALDH1A1 (0.66) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL8407368 0.91 ALDH1A1 (0.66) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL28394623 0.91 ALDH1A1 (0.66) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL11360223 0.91 ALDH1A1 (0.66) ALDH1A1LMNAUSP2POLBHTT
SCHEMBL10245113 0.89 ALDH1A1 (0.63) ALDH1A1LMNAUSP2POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118145943-B Precast pile installation method 中国兵器工业北方勘察设计研究院有限公司 2024-07-12 CN disclosed
CN-118145943-A Precast pile installation method 中国兵器工业北方勘察设计研究院有限公司 2024-06-07 CN disclosed
US-7514507-B2 Comb-shaped epoxy resin and method for preparing comb-shaped epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-04-07 US disclosed
US-20070142611-A1 Comb-shaped epoxy resin and method for preparing comb-shaped epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-21 US disclosed