Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453198 | 0.86 | CYP19A1 (0.40) | MAPTCYP19A1NAMPT | |
| SCHEMBL3201561 | 0.84 | SCN9A (0.47) | SCN9AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL3214632 | 0.83 | SCN9A (0.46) | SCN9AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL3201301 | 0.82 | SCN9A (0.48) | SCN9AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL3210207 | 0.80 | CYP19A1 (0.63) | SCN9ASMN1; SMN2POLBCYP19A1 | |
| SCHEMBL3196894 | 0.75 | SCN9A (0.44) | SCN9ASMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL13486211 | 0.73 | BRD4 (0.42) | MAPTSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL14386835 | 0.71 | ALDH1A1 (0.53) | SMN1; SMN2KMT2ACYP19A1HTT | |
| SCHEMBL14387086 | 0.70 | ALDH1A1 (0.55) | SMN1; SMN2KMT2ACYP19A1HTT | |
| SCHEMBL3204885 | 0.70 | MRGPRX4 (0.43) | MAPTSMN1; SMN2MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010495-A2 | NEW HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | Mutabilis SA (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007135562-A2 | HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS S.A. (FR) | 2007-11-29 | — | — | WO | disclosed |