SCHEMBL4453307

SCHEMBL4453307

Clc1ccc(-c2c(Cl)ccc(Cl)c2Cl)c(Cl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.52
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 2/20 0.39
CES1 P23141 2/20 0.35
PTGS2 P35354 1/20 0.33
ALPL P05186 2/20 0.33
CYP2A6 P11509 1/20 0.32
ALDH1A1 P00352 2/20 0.30
ADORA2A P29274 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
APEX1 P27695 1/20 0.30
RECQL P46063 1/20 0.30
RAB9A P51151 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492227 1.00 AHR (0.52) AHRCYP3A4MAPK1TDP1CES1
SCHEMBL4450510 0.84 AHR (0.48) AHRCYP3A4MAPK1TDP1CYP2A6
SCHEMBL5685708 0.84 AHR (0.60) AHRCYP3A4MAPK1TDP1CES1
SCHEMBL30301086 0.83 AHR (0.52) AHRCYP3A4MAPK1TDP1CES1
SCHEMBL2230317 0.83 AHR (0.52) AHRCYP3A4MAPK1TDP1CES1
SCHEMBL29624836 0.82 AHR (0.54) AHRCYP3A4MAPK1TDP1CES1
SCHEMBL4449764 0.82 AHR (0.54) AHRCYP3A4MAPK1TDP1CES1
SCHEMBL4449569 0.82 AHR (0.58) AHRCYP3A4MAPK1TDP1ALPL
SCHEMBL308791 0.82 AHR (0.62) AHRCYP3A4MAPK1TDP1CES1
Water SCHEMBL11727747 0.81 AHR (0.50) AHRCYP3A4MAPK1TDP1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed