SCHEMBL5685708

SCHEMBL5685708

Clc1ccc(-c2c(Cl)c(Cl)cc(Cl)c2Cl)c(Cl)c1Cl

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AHR P35869 9/20 0.60
CYP3A4 P08684 2/20 0.48
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 2/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TDP1 Q9NUW8 1/20 0.37
CASP1 P29466 1/20 0.36
CYP1B1 Q16678 1/20 0.36
ALPL P05186 1/20 0.34
CES1 P23141 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449569 0.88 AHR (0.58) AHRCYP3A4ALDH1A1MAPK1HPGD
SCHEMBL2230317 0.84 AHR (0.52) AHRCYP3A4ALDH1A1MAPK1HPGD
SCHEMBL4453307 0.84 AHR (0.52) AHRCYP3A4ALDH1A1MAPK1TDP1
SCHEMBL30301086 0.84 AHR (0.52) AHRCYP3A4ALDH1A1MAPK1HPGD
SCHEMBL29492227 0.84 AHR (0.52) AHRCYP3A4ALDH1A1MAPK1TDP1
Water SCHEMBL11727747 0.82 AHR (0.50) AHRCYP3A4MAPK1TDP1ALPL
SCHEMBL4459649 0.80 AHR (0.54) AHRCYP3A4ALDH1A1MAPK1HPGD
SCHEMBL4456805 0.79 CYP3A4 (0.61) AHRCYP3A4ALDH1A1MAPK1HPGD
SCHEMBL30035000 0.79 CYP3A4 (0.61) AHRCYP3A4ALDH1A1MAPK1HPGD
SCHEMBL4449764 0.78 AHR (0.54) AHRCYP3A4ALDH1A1MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220351865-A1 METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS GERO PTE. LTD. (SG) 2022-11-03 US claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-116482813-B Compact micro-platform for optical transceiver assembly 云晖科技有限公司 2026-02-27 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-116482813-A Compact micro-platform for optical transceiver assembly 东莞云晖光电有限公司 2023-07-25 CN disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
US-20220351865-A1 METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS GERO PTE. LTD. (SG) 2022-11-03 US disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
EP-1616022-A2 TEST SYSTEM FOR DETECTING CONTAMINANTS Crown Vision Systems Limited (GB) 2006-01-18 EP disclosed
WO-2004090156-A2 TEST SYSTEM FOR DETECTING CONTAMINANTS CROWN VISION SYSTEMS LIMITED (GB) 2004-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES PFKFB3, PFKFB4, PFKFB1 AHR 3353/4885CYP3A4 2539/4885ALDH1A1 1943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.