Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453330 | 1.00 | ELANE (0.49) | ELANENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4461483 | 0.91 | ELANE (0.53) | ELANENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4456597 | 0.91 | ELANE (0.53) | ELANENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4453282 | 0.89 | NPC1 (0.43) | ELANENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4457207 | 0.87 | ELANE (0.52) | ELANENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4459938 | 0.86 | ELANE (0.48) | ELANENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL13606504 | 0.86 | ELANE (0.48) | ELANENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4459935 | 0.86 | ELANE (0.48) | ELANENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4458412 | 0.85 | CTSL (0.44) | ELANECTSS | |
| SCHEMBL4458411 | 0.85 | CTSL (0.44) | ELANECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |