Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336074 | 0.87 | KDM4E (0.47) | KDM4EMAPK1HSD17B10MAPTLMNA | |
| SCHEMBL4336070 | 0.87 | KDM4E (0.47) | KDM4EMAPK1HSD17B10MAPTLMNA | |
| SCHEMBL4457837 | 0.84 | KDM4E (0.51) | KDM4EMAPK1HSD17B10MAPTLMNA | |
| SCHEMBL4455856 | 0.81 | KMT2A (0.60) | KDM4EMAPK1HSD17B10MAPTLMNA | |
| SCHEMBL4323303 | 0.80 | KDM4E (0.42) | KDM4EMAPK1HSD17B10MAPTLMNA | |
| SCHEMBL4455963 | 0.80 | KDM4E (0.51) | KDM4EMAPK1HSD17B10MAPTLMNA | |
| SCHEMBL4329435 | 0.76 | MAPT (0.58) | KDM4EMAPK1HSD17B10MAPTLMNA | |
| SCHEMBL4324521 | 0.74 | MAPT (0.81) | KDM4EMAPK1MAPTLMNAMEN1 | |
| SCHEMBL4324519 | 0.74 | MAPT (0.81) | KDM4EMAPK1MAPTLMNAMEN1 | |
| SCHEMBL4341378 | 0.74 | MAPT (0.48) | KDM4EMAPK1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |