Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341464 | 0.88 | MAPT (0.49) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL4341461 | 0.88 | MAPT (0.49) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL4455856 | 0.85 | KMT2A (0.60) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL4343477 | 0.84 | KDM4E (0.57) | KDM4EHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL4334594 | 0.81 | MAPT (0.46) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL4329481 | 0.80 | KDM4E (0.44) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL4329090 | 0.80 | ALDH1A1 (0.52) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL4334744 | 0.80 | ALDH1A1 (0.52) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL4453469 | 0.80 | KDM4E (0.49) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL4461761 | 0.79 | MAPT (0.49) | KDM4EHPGDHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |