Ethylene Glycol

Ethylene Glycol

SCHEMBL4453630

C=Cc1cccc(C=C)c1C=C.OCCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
SLC9A1 P19634 2/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CHAT P28329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1930128 0.89 ALDH1A1 (0.35) ALDH1A1HPGDTSHRHSD17B10
SCHEMBL18301 0.87 ALDH1A1 (0.48) ALDH1A1SLC9A1TSHR
Benzene SCHEMBL3430618 0.85 ALDH1A1 (0.46) ALDH1A1SLC9A1TSHR
SCHEMBL28917788 0.85 ALDH1A1 (0.46) ALDH1A1SLC9A1TSHR
Butadiene SCHEMBL27714941 0.82 ALDH1A1 (0.44) ALDH1A1SLC9A1TSHR
SCHEMBL8440886 0.82 ALDH1A1 (0.50) ALDH1A1SLC9A1HPGDTSHRMAPK1
Ethylene Glycol SCHEMBL640721 0.82 ALDH1A1 (0.50) ALDH1A1HPGDTSHRMAPK1HSD17B10
Bicarbonate SCHEMBL10785635 0.81 ALDH1A1 (0.39) ALDH1A1SLC9A1TSHR
SCHEMBL16955257 0.81 ALDH1A1 (0.39) ALDH1A1SLC9A1
1,1-Dichloroethene SCHEMBL28747258 0.81 ALDH1A1 (0.44) ALDH1A1SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120211439-A1 SCAVENGER SUPPORTS AND THE USE THEREOF IN A PROCESS FOR THE EXTRACTION OF METALS JOHNSON MATTHEY FINLAND OY (FI) 2012-08-23 US claimed
US-20090023604-A1 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2009-01-22 US claimed
EP-1769094-B1 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOAMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS REAXA LTD (GB) 2008-12-10 EP claimed
EP-1769094-A2 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOAMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS Reaxa Limited (GB) 2007-04-04 EP claimed
EP-1299429-B1 SCAVENGER RESIN AND PROCESSES FOR THE USE THEREOF REAXA LTD (GB) 2007-03-07 EP claimed
WO-2005123971-A2 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS REAXA LIMITED (GB) 2005-12-29 WO claimed
US-6897262-B2 For removing primary amines from solution, removal of electrophiles, a copolymer of acetoacetoxyethyl methacrylate, styrene and divinylbenzene; solid phase synthesis, removing benzylamine AVECIA LIMITED (GB) 2005-05-24 US claimed
US-20040082707-A1 Electrophilic activity; removal primary amines form solution JOHNSON MATTHEY FINLAND OY (FI) 2004-04-29 US claimed
EP-1299429-A1 SCAVENGER RESIN AND PROCESSES FOR THE USE THEREOF Avecia Limited (GB) 2003-04-09 EP claimed
WO-2001098378-A1 SCAVENGER RESIN AND PROCESSES FOR THE USE THEREOF AVECIA LIMITED (GB) 2001-12-27 WO claimed
US-9234256-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2016-01-12 US disclosed
US-8652335-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2014-02-18 US disclosed
US-20120211439-A1 SCAVENGER SUPPORTS AND THE USE THEREOF IN A PROCESS FOR THE EXTRACTION OF METALS JOHNSON MATTHEY FINLAND OY (FI) 2012-08-23 US disclosed
US-20090023604-A1 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2009-01-22 US disclosed
EP-1769094-B1 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOAMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS REAXA LTD (GB) 2008-12-10 EP disclosed
WO-2005123971-A2 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS REAXA LIMITED (GB) 2005-12-29 WO disclosed
US-6897262-B2 For removing primary amines from solution, removal of electrophiles, a copolymer of acetoacetoxyethyl methacrylate, styrene and divinylbenzene; solid phase synthesis, removing benzylamine AVECIA LIMITED (GB) 2005-05-24 US disclosed
US-20040082707-A1 Electrophilic activity; removal primary amines form solution JOHNSON MATTHEY FINLAND OY (FI) 2004-04-29 US disclosed
EP-1299429-A1 SCAVENGER RESIN AND PROCESSES FOR THE USE THEREOF Avecia Limited (GB) 2003-04-09 EP disclosed
WO-2001098378-A1 SCAVENGER RESIN AND PROCESSES FOR THE USE THEREOF AVECIA LIMITED (GB) 2001-12-27 WO disclosed