⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23329 | 0.74 | — | — | |
| SCHEMBL47587 | 0.74 | — | — | |
| SCHEMBL20798905 | 0.74 | — | — | |
| SCHEMBL21195124 | 0.70 | — | — | |
| SCHEMBL20581667 | 0.70 | — | — | |
| SCHEMBL1170851 | 0.67 | — | — | |
| SCHEMBL8164329 | 0.65 | — | — | |
| SCHEMBL5047343 | 0.59 | — | — | |
| SCHEMBL3083314 | 0.59 | ALDH1A1 (0.30) | — | |
| SCHEMBL4076637 | 0.59 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116656795-A | Nucleotide derivatives and methods of use thereof | 纽约哥伦比亚大学董事会 | 2023-08-29 | — | — | CN | claimed |
| US-20180327828-A1 | ION SENSOR DNA AND RNA SEQUENCING BY SYNTHESIS USING NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-11-15 | — | — | US | claimed |
| US-12006540-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-06-11 | — | — | US | disclosed |
| US-11999999-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-06-04 | — | — | US | disclosed |
| US-20240174709-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-05-30 | — | — | US | disclosed |
| WO-2024101446-A1 | MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME | ルクサナバイオテク株式会社 | 2024-05-16 | — | — | WO | disclosed |
| US-11958877-B2 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2024-04-16 | — | — | US | disclosed |
| US-11959137-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-04-16 | — | — | US | disclosed |
| US-11878993-B2 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2024-01-23 | — | — | US | disclosed |
| CN-117229330-A | Application of silica microsphere in synthesis of ultralong oligonucleotide and method for synthesizing ultralong oligonucleotide | 上海交通大学 | 2023-12-15 | — | — | CN | disclosed |
| US-20230340008-A1 | BRIDGED NUCLEOSIDE AND NUCLEOTIDE USING SAME | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF HEALTH SCIENCES (JP) | 2023-10-26 | — | — | US | disclosed |
| EP-1412437-B1 | BINDING AGENT COMPONENT FOR SURFACE COATING AGENTS WITH IMPROVED ADHESIVE PROPERTIES | HENKEL KGAA (DE) | 2007-09-12 | — | — | EP | disclosed |
| EP-1227094-B1 | Isocyanurate compound and method for producing the same | NISSAN CHEMICAL IND LTD (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-20050129955-A1 | Binding agent component for surface coating agents with improved adhesive properties | HENKEL AG & CO. KGAA (DE) | 2005-06-16 | — | — | US | disclosed |
| US-20020161223-A1 | Isocyanurate compound and method for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1227094-A1 | Isocyanurate compound and method for producing the same | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |
| US-6414146-B1 | TRIS(1,3-OXATHIOLANE-2-THION-5-YLMETHYL)ISOCYANURATE OR TRIS(5-METHYL-1,3-OXATHIOLANE-2-THION-5-YLMETHYL)ISOCYANURATE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |