SCHEMBL4453779

SCHEMBL4453779

O=C(O)CCCC=CCCCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.67
PPARD Q03181 5/20 0.67
PPARA Q07869 5/20 0.67
TOP1 P11387 3/20 0.67
CYP19A1 P11511 3/20 0.67
KMT2A Q03164 3/20 0.67
F7 P08709 3/20 0.67
F3 P13726 3/20 0.67
ALDH1A1 P00352 2/20 0.67
ADORA3 P0DMS8 2/20 0.67
PTGS1 P23219 2/20 0.67
RXRA P19793 1/20 0.67
OXER1 Q8TDS5 1/20 0.67
MAPT P10636 3/20 0.64
FABP4 P15090 3/20 0.64
BLM P54132 3/20 0.64
HSD17B10 Q99714 3/20 0.64
LMNA P02545 3/20 0.64
USP2 O75604 2/20 0.64
ALOX15 P16050 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18035212 1.00 PPARG (0.67) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL4453776 1.00 PPARG (0.67) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL6439962 0.94 PPARG (0.61) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL16965088 0.94 PPARG (0.71) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL6439966 0.94 PPARG (0.61) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL23191717 0.94 PPARG (0.61) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL16965087 0.94 PPARG (0.71) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL5410794 0.92 PPARG (0.75) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL5272057 0.92 PPARG (0.75) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL11048809 0.92 PPARG (0.75) PPARGPPARDPPARATOP1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5326850-A Radiation crosslinking, high heat deflection temperature BASF AKTIENGESELLSCHAFT (DE) 1994-07-05 US claimed
US-5266656-A Blends of polyamides and polyamides with olefin bonds BASF AKTIENGESELLSCHAFT (DE) 1993-11-30 US claimed
CN-117434167-A Detection method for related substances in michaeli ammonium chloride 四川科瑞德制药股份有限公司 2024-01-23 CN disclosed
CN-117434166-A (E) Method for detecting impurities in-octyl-4-ene-1, 8-diacid 四川科瑞德制药股份有限公司 2024-01-23 CN disclosed
CN-117430498-A (E) Process for preparing oct-4-ene-1, 8-dioic acid 四川科瑞德制药股份有限公司 2024-01-23 CN disclosed
US-10906861-B2 Methods of making organic compounds by metathesis WILMAR TRADING PTE LTD (SG) 2021-02-02 US disclosed
CN-105829328-B Method for synthesizing alkanes -1- hydroxyl -1,1- di 2 ethylhexyl phosphonic acid 孟山都技术有限责任公司 2019-02-19 CN disclosed
EP-3060567-B1 METHOD FOR THE SYNTHESIS OF ALKANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID STRAITMARK HOLDING AG (CH) 2018-12-05 EP disclosed
EP-3281931-A1 METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS Elevance Renewable Sciences, Inc. (US) 2018-02-14 EP disclosed
EP-3015450-B1 Hydrophilic antioxidant and method for the preparation of the same FOUNDER FINE CHEMICAL IND CO LTD (TW) 2017-01-04 EP disclosed
EP-3061746-B1 HYDROPHILIC ANTIOXIDANT AND PROCESS FOR THE PREPARATION OF THE SAME FOUNDER FINE CHEMICAL IND CO LTD (TW) 2016-12-07 EP disclosed
US-5326850-A Radiation crosslinking, high heat deflection temperature BASF AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
US-5266656-A Blends of polyamides and polyamides with olefin bonds BASF AKTIENGESELLSCHAFT (DE) 1993-11-30 US disclosed
US-4221605-A Sulfur foam process CHEVRON RESEARCH COMPANY (US) 1980-09-09 US disclosed
US-4111864-A SULFUR FOAM CHEVRON RESEARCH COMPANY (US) 1978-09-05 US disclosed
US-4079023-A Sulfur foam process and product CHEVRON RESEARCH COMPANY (US) 1978-03-14 US disclosed
US-4014922-A CYCLOPROPYL SUBSTITUTED ESTERS; MITICIDES ZOECON CORPORATION (US) 1977-03-29 US disclosed
US-4011179-A CONTINUOUS SULFUR FOAM PREPARATION USING POLYISOCYANATES CHEVRON RESEARCH COMPANY (US) 1977-03-08 US disclosed
US-3954685-A Sulfur foam product and process CHEVRON RESEARCH COMPANY (US) 1976-05-04 US disclosed
US-3948961-A CYCLOPROPYL ALKYL CARBOXYLATES, MITICIDE, INSECTICIDE ZOECON CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10906861-B2 Methods of making organic compounds by metathesis COASY, FASN, HAO2 PPARG 1388/4885PPARD 352/4885PPARA 879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.