SCHEMBL4453840

SCHEMBL4453840

CCCCCCCCN([O])CCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 6/20 0.55
TSHR P16473 2/20 0.50
THRB P10828 1/20 0.50
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
S1PR2 O95136 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
S1PR5 Q9H228 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
GBA1 P04062 1/20 0.39
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
EPHX2 P34913 1/20 0.39
GGPS1 O95749 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811342 1.00 DNM1 (0.55) DNM1TSHRTHRBCA12CA1
SCHEMBL22806344 0.97 DNM1 (0.52) DNM1TSHRTHRBCA12CA1
SCHEMBL1239128 0.97 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL22806345 0.94 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL22806261 0.88 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL8001833 0.87 CA1 (0.42) DNM1TSHRTHRBCA12CA1
SCHEMBL28701706 0.81 DNM1 (0.63) DNM1TSHRTHRBCA12CA1
SCHEMBL24113600 0.73 DNM1 (0.61) DNM1TSHRTHRBCA12CA1
SCHEMBL36579 0.73 DNM1 (0.61) DNM1TSHRTHRBCA12CA1
SCHEMBL7072477 0.73 DNM1 (0.61) DNM1TSHRTHRBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999852-B2 Use of aryl group containing organopolysiloxane gums as additives to increase rheological behavior Elkem Silicones USA Corp. 2024-06-04 US disclosed
US-20240109256-A1 A METHOD OF ADDITIVE MANUFACTURE OF A THREE-DIMENSIONAL ARTICLE MADE OF A CURED MATERIAL AND A GEL LIKE SUPPORT FOR USE IN ADDITIVE MANUFACTURING ELKEM SILICONES FRANCE SAS (FR) 2024-04-04 US disclosed
EP-3790724-B1 METHOD FOR MANUFACTURING A SILICONE ELASTOMER ARTICLE USING A 3D PRINTER ELKEM SILICONES FRANCE SAS (FR) 2023-12-13 EP disclosed
EP-4288493-A1 A METHOD OF ADDITIVE MANUFACTURE OF A THREE-DIMENSIONAL ARTICLE MADE OF A CURED MATERIAL AND A GEL LIKE SUPPORT FOR USE IN ADDITIVE MANUFACTURING Elkem Silicones France SAS (FR) 2023-12-13 EP disclosed
CN-116829649-A Additive manufacturing method of three-dimensional article made of cured material and gel-like support material used in additive manufacturing 埃肯有机硅法国简易股份公司 2023-09-29 CN disclosed
US-20230295428-A1 CROSSLINKABLE SILICONE ELASTOMER COMPOSITION CONTAINING A HEAT-RESISTANT ADDITIVE ELKEM SILICONES FRANCE SAS (FR) 2023-09-21 US disclosed
US-11760890-B2 Method for the additive manufacturing of a silicone elastomer article ELKEM SILICONES FRANCE SAS (FR) 2023-09-19 US disclosed
CN-116635217-A Method of manufacturing silicone elastomer articles using 3D printer 埃肯有机硅法国简易股份公司 2023-08-22 CN disclosed
US-20230250285-A1 USE OF ARYL GROUP CONTAINING ORGANOPOLYSILOXANE GUMS AS ADDITIVES TO INCREASE RHEOLOGICAL BEHAVIOR Elkem Silicones USA Corp. 2023-08-10 US disclosed
WO-2023123482-A1 TWO-PART SILICONE COMPOSITION FOR ADDITIVE MANUFACTURING ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2023-07-06 WO disclosed
EP-0018634-A1 Compositions cross-linkable into elastomers Wacker-Chemie GmbH (DE) 1980-11-12 EP disclosed
US-4230826-A COMPRISING A POLYSILOXANE, A SILICON CROSSLINKING AGENT, AND A POLYMER OF ACRYLONITRILE; MOISTURE-CURED WACKER-CHEMIE GMBH (DE) 1980-10-28 US disclosed
US-4211729-A Compositions containing diorganopolysiloxanes CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE, GMBH (DE) 1980-07-08 US disclosed
EP-0005786-A1 Elastomers obtained from crosslinkable compositions Wacker-Chemie GmbH (DE) 1979-12-12 EP disclosed
US-4152343-A REACTING AN ORGANIC SILICATE OR SILANETRIOL DERIVATIVE WITH A DIALKYLTIN CAROXYLIC ACID SALT WACKER-CHEMIE GMBH (DE) 1979-05-01 US disclosed
US-4137249-A Silicon-tin compounds WACKER-CHEMIE GMBH (DE) 1979-01-30 US disclosed
US-4102860-A ROOM TEMPERATURE CURING WACKER-CHEMIE GMBH (DE) 1978-07-25 US disclosed
US-4076684-A GLASS FIBERS; CURABLE WACKER-CHEMIE GMBH (DT) 1978-02-28 US disclosed
US-4045602-A ADHESION OF ORGANOPOLYSILOXANE ELASTOMERS TO SUBSTRATES WACKER-CHEMIE GMBH (DT) 1977-08-30 US disclosed
US-4026853-A Curable bituminous organopolysiloxane compositions CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DT) 1977-05-31 US disclosed