SCHEMBL4453878

SCHEMBL4453878

O=P(O)(Oc1ccccc1)Oc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.53
LTA4H P09960 1/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
ESR2 Q92731 2/20 0.44
GPR84 Q9NQS5 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ESR1 P03372 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6429907 0.98 SRC (0.55) SRCLTA4HNR1H2BAXMMP3
SCHEMBL6118470 0.96 MMP3 (0.56) SRCLTA4HNR1H2BAXMMP3
SCHEMBL5512108 0.94 SRC (0.59) SRCLTA4HNR1H2BAXCES2
Hydroquinone SCHEMBL1319492 0.92 SRC (0.61) SRCLTA4HNR1H2BAXCES2
SCHEMBL22015739 0.90 SRC (0.59) SRCCES2CES1GPR84TDP1
Phenol SCHEMBL28209872 0.88 SRC (0.61) SRCLTA4HNR1H2BAXCES2
Phenol SCHEMBL14793565 0.88 SRC (0.61) SRCLTA4HNR1H2BAXCES2
SCHEMBL7175071 0.88 SRC (0.56) SRCCES2CES1RAB9AGPR84
SCHEMBL14718052 0.87 SRC (0.55) SRCLTA4HNR1H2BAXCES2
SCHEMBL6429904 0.87 MMP3 (0.52) SRCLTA4HNR1H2BAXMMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1327635-B1 Preparation of phenylphosphate esters of 4,4'-biphenol BROMINE COMPOUNDS LTD (IL) 2005-08-31 EP claimed
US-20030171463-A1 Preparation of phenylphosphate esters of 4,4'-biphenol BROMINE COMPOUNDS LTD. (IL) 2003-09-11 US claimed
EP-1327635-A1 Preparation of phenylphosphate esters of 4,4'-biphenol Bromine Compounds Ltd. (IL) 2003-07-16 EP claimed
EP-3037483-B1 FLAME-RETARDANT SYNTHETIC RESIN COMPOSITION ADEKA CORP (JP) 2017-09-06 EP disclosed
EP-1773744-B1 SYNTHESIS OF PENTABROMOBENZYL BROMIDE (PBB-Br) BROMINE COMPOUNDS LTD (IL) 2013-01-16 EP disclosed
US-7601774-B2 Synthesis of aromatic polyhalogenated halomethyl compounds BROMINE COMPOUNDS LTD. (IL) 2009-10-13 US disclosed
US-7585912-B2 Flame-retardant polystyrenes BROMINE COMPOUNDS LTD. (IL) 2009-09-08 US disclosed
EP-1786853-B1 NOVEL FLAME-RETARDANT POLYSTYRENES BROMINE COMPOUNDS LTD (IL) 2009-04-15 EP disclosed
US-20070257241-A1 Novel Flame-Retardant Polystyrenes BROMINE COMPOUNDS LTD. (IL) 2007-11-08 US disclosed
US-20070205403-A1 Synthesis of Aromatic Polyhalogenated Halomethyl Compounds BROMINE COMPOUNDS LTD. (IL) 2007-09-06 US disclosed
EP-1786853-A1 NOVEL FLAME-RETARDANT POLYSTYRENES Bromine Compounds Ltd. (IL) 2007-05-23 EP disclosed
EP-1773744-A1 SYNTHESIS OF AROMATIC POLYHALOGENATED HALOMETHYL COMPOUNDS Bromine Compounds Ltd. (IL) 2007-04-18 EP disclosed
WO-2006013554-A1 NOVEL FLAME-RETARDANT POLYSTYRENES BROMINE COMPOUNDS LTD. (IL) 2006-02-09 WO disclosed
WO-2006008738-A1 SYNTHESIS OF AROMATIC POLYHALOGENATED HALOMETHYL COMPOUNDS BROMINE COMPOUNDS LTD. (IL) 2006-01-26 WO disclosed
US-20050130251-A1 Reagent for determination of hydrogen peroxide KYOWA MEDEX CO., LTD. (JP) 2005-06-16 US disclosed
EP-1424554-A1 REAGENT FOR DETERMINING HYDROGEN PEROXIDE KYOWA MEDEX CO., LTD. (JP) 2004-06-02 EP disclosed
US-20030171463-A1 Preparation of phenylphosphate esters of 4,4'-biphenol BROMINE COMPOUNDS LTD. (IL) 2003-09-11 US disclosed
EP-1327635-A1 Preparation of phenylphosphate esters of 4,4'-biphenol Bromine Compounds Ltd. (IL) 2003-07-16 EP disclosed