⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788864 | 0.70 | CYP2D6 (0.44) | — | |
| SCHEMBL29788853 | 0.70 | CYP2D6 (0.44) | — | |
| SCHEMBL29788839 | 0.70 | CYP2D6 (0.44) | — | |
| SCHEMBL28691021 | 0.69 | GAA (0.40) | — | |
| SCHEMBL29957128 | 0.69 | GAA (0.40) | — | |
| SCHEMBL18699237 | 0.69 | GAA (0.40) | — | |
| SCHEMBL29788850 | 0.68 | CYP19A1 (0.48) | — | |
| SCHEMBL5015042 | 0.67 | — | — | |
| SCHEMBL10637369 | 0.65 | GAA (0.37) | — | |
| SCHEMBL7018114 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687988-B1 | ANTIBACTERIAL COMPOUND AND USES OF SAME | BIOMERIEUX SA (FR) | 2023-05-03 | — | — | EP | disclosed |
| US-11414403-B2 | Antibacterial compound and uses of same | BIOMERIEUX (FR) | 2022-08-16 | — | — | US | disclosed |
| EP-3774734-A1 | COMPOUNDS FOR TREATMENT OF CARDIAC ARRHYTHMIAS AND HEART FAILURE | Elex Biotech, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20200277281-A1 | ANTIBACTERIAL COMPOUND AND USES OF SAME | bioMérieux (FR) | 2020-09-03 | — | — | US | disclosed |
| EP-3687988-A1 | ANTIBACTERIAL COMPOUND AND USES OF SAME | bioMérieux (FR) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019191502-A1 | COMPOUNDS FOR TREATMENT OF CARDIAC ARRHYTHMIAS AND HEART FAILURE | ELEX BIOTECH, INC. (US) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019058074-A1 | ANTIBACTERIAL COMPOUND AND USES OF SAME | bioMérieux (FR) | 2019-03-28 | — | — | WO | disclosed |
| EP-0819000-B1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-0819000-A4 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| US-5962499-A | ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1999-10-05 | — | — | US | disclosed |
| CN-1184423-A | Nodulisporic acid derivatives | MERCK & CO INC (US) | 1998-06-10 | — | — | CN | disclosed |
| EP-0819000-A1 | NODULISPORIC ACID DERIVATIVES | Merck & Co., Inc. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996029073-A1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1996-09-26 | — | — | WO | disclosed |