Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13090818 | 0.78 | — | — | |
| SCHEMBL3587455 | 0.71 | CYP19A1 (0.37) | NOTUM | |
| SCHEMBL4454073 | 0.69 | — | — | |
| SCHEMBL9596326 | 0.69 | — | — | |
| SCHEMBL24027141 | 0.64 | ALDH1A1 (0.50) | GAAALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL28691021 | 0.62 | GAA (0.40) | GAAALDH1A1NOTUM | |
| SCHEMBL29957128 | 0.62 | GAA (0.40) | GAAALDH1A1NOTUM | |
| SCHEMBL7563172 | 0.62 | HRH1 (0.34) | MEN1KMT2A | |
| SCHEMBL4685599 | 0.62 | — | — | |
| SCHEMBL18812115 | 0.61 | DPP4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611213-B2 | Functionalized 1,3-benzene diols and their method of use for the treatment of hepatic encephalopathy | KANNALIFE SCIENCES, INC. (US) | 2017-04-04 | — | — | US | disclosed |