Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501570 | 0.93 | LMNA (0.42) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL25437774 | 0.93 | LMNA (0.42) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL4448715 | 0.93 | LMNA (0.42) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL23355933 | 0.93 | LMNA (0.42) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL12231695 | 0.93 | LMNA (0.42) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL9633841 | 0.91 | LMNA (0.43) | ALDH1A1HTTMEN1THRBKMT2A | |
| Alcohol SCHEMBL4556413 | 0.86 | PLA2G2C (0.39) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL90420 | 0.84 | — | — | |
| SCHEMBL18193401 | 0.82 | LMNA (0.40) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL26232738 | 0.82 | HTT (0.37) | ALDH1A1HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663916-B1 | METHOD FOR CATALYTIC DEOXYGENATION OF PROCESS FLUIDS OF OLEFIN DIMERIZATION PROCESSES | NESTE OIL OYJ (FI) | 2009-07-01 | — | — | EP | disclosed |