Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.62 |
| ▸ | PGR | P06401 | 12/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15135768 | 0.90 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL291534 | 0.85 | NR3C1 (0.76) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4448705 | 0.84 | NR3C1 (0.56) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL6385024 | 0.84 | NR3C1 (0.52) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3687823 | 0.83 | NR3C1 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL5255163 | 0.82 | NR3C1 (0.74) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292642 | 0.77 | NR3C1 (0.82) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL299927 | 0.76 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292902 | 0.76 | NR3C1 (0.87) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1634081 | 0.76 | NR3C1 (0.85) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051736-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST AND AN IMMUNOSUPPRESSIVE AGENT FOR TREATING DRY EYE | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008005686-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST AND AN IMMUNOSUPPRESSIVE AGENT FOR TREATING DRY EYE | BAUSCH & LOMB INCORPORATED (US) | 2008-01-10 | — | — | WO | disclosed |