⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2923012 | 0.97 | — | — | |
| Acetic Acid SCHEMBL4452287 | 0.85 | GAA (0.33) | — | |
| Hydrochloric Acid SCHEMBL8467105 | 0.82 | — | — | |
| SCHEMBL7678958 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7683971 | 0.74 | — | — | |
| SCHEMBL14045629 | 0.71 | — | — | |
| SCHEMBL90056 | 0.67 | — | — | |
| SCHEMBL3831112 | 0.67 | — | — | |
| SCHEMBL77344 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL29493442 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312203-A1 | Bicyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors | WYETH (US) | 2008-12-18 | — | — | US | claimed |
| US-20240336611-A1 | ANALOGS FOR THE TREATMENT OF DISEASE | INSILICO MEDICINE IP LIMITED (HK) | 2024-10-10 | — | — | US | disclosed |
| EP-4298094-A1 | ANALOGS FOR THE TREATMENT OF DISEASE | Insilico Medicine IP Limited (HK) | 2024-01-03 | — | — | EP | disclosed |
| CN-117222642-A | Analogues for the treatment of disease | 英矽智能科技知识产权有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-11834449-B2 | TYK2 inhibitors and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-12-05 | — | — | US | disclosed |
| CN-113423262-B | Flowable concentrate composition for agricultural seeds | 陶氏环球技术有限责任公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116726178-A | Use of sGC stimulators in the treatment of non-alcoholic steatohepatitis (NASH) | 赛克里翁治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022179529-A1 | ANALOGS FOR THE TREATMENT OF DISEASE | INSILICO MEDICINE IP LIMITED (CN) | 2022-09-01 | — | — | WO | disclosed |
| US-11053241-B2 | TYK2 inhibitors and uses thereof | NIMBUS LAKSHMI, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| US-20200172540-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-06-04 | — | — | US | disclosed |
| WO-2020112937-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| US-20090018332-A1 | Processes For Preparing Bicyclic Oxazine Carboxaldehyde and Beta-Lactamase Inhibitors | WYETH (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018332-A1 | Processes For Preparing Bicyclic Oxazine Carboxaldehyde and Beta-Lactamase Inhibitors | WYETH (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018332-A1 | Processes For Preparing Bicyclic Oxazine Carboxaldehyde and Beta-Lactamase Inhibitors | WYETH (US) | 2009-01-15 | — | — | US | disclosed |
| WO-2009006243-A2 | PROCESSES FOR PREPARING BICYCLIC OXAZINE CARBOXALDEHYDE AND BETA-LACTAMASE INHIBITORS | WYETH (US) | 2009-01-08 | — | — | WO | disclosed |
| WO-2009006243-A2 | PROCESSES FOR PREPARING BICYCLIC OXAZINE CARBOXALDEHYDE AND BETA-LACTAMASE INHIBITORS | WYETH (US) | 2009-01-08 | — | — | WO | disclosed |