Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453346 | 0.85 | SIGMAR1 (0.38) | SIGMAR1CYP1A2 | |
| SCHEMBL4816692 | 0.67 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL5450869 | 0.64 | CYP1A2 (0.48) | SIGMAR1CYP1A2 | |
| SCHEMBL15355135 | 0.64 | CYP1A2 (0.48) | SIGMAR1CYP1A2 | |
| SCHEMBL6153538 | 0.64 | CYP1A2 (0.48) | SIGMAR1CYP1A2 | |
| SCHEMBL3835776 | 0.63 | CYP1A2 (0.46) | SIGMAR1CYP1A2 | |
| SCHEMBL6583190 | 0.62 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL60655 | 0.61 | CYP1A2 (0.58) | SIGMAR1CYP1A2 | |
| SCHEMBL2573209 | 0.61 | CYP1A2 (0.58) | SIGMAR1CYP1A2 | |
| SCHEMBL5617552 | 0.61 | CYP1A2 (0.58) | SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670852-B1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INT (FR) | 2008-12-10 | — | — | EP | claimed |
| US-20060270771-A1 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2006-11-30 | — | — | US | claimed |
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| EP-1670852-B1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INT (FR) | 2008-12-10 | — | — | EP | disclosed |
| US-20060270771-A1 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2006-11-30 | — | — | US | disclosed |