SCHEMBL4454643

SCHEMBL4454643

CCO[SiH2]C1CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5930917 0.78 KDM4E (0.31) KDM4EALDH1A1
SCHEMBL4603489 0.77
SCHEMBL6062716 0.75 KDM4E (0.32) KDM4EALDH1A1
SCHEMBL5701938 0.75
SCHEMBL5701689 0.74
SCHEMBL7528660 0.74 KDM4E (0.31) KDM4E
SCHEMBL5435943 0.73 KDM4E (0.32) KDM4EALDH1A1
SCHEMBL5442559 0.73
SCHEMBL6062891 0.73 KDM4E (0.33) KDM4EALDH1A1
SCHEMBL5701659 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170196897-A1 COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE EPIDERMAL DISEASES DERMIPSOR LTD. (IL) 2017-07-13 US disclosed
US-9603861-B2 Compositions and methods for treating hyperproliferative epidermal diseases DERMIPSOR LTD. (IL) 2017-03-28 US disclosed
US-20160015723-A1 COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE EPIDERMAL DISEASES DERMIPSOR LTD. (IL) 2016-01-21 US disclosed
US-9173835-B2 Compositions and methods for treating hyperproliferative epidermal diseases DERMIPSOR LTD. (IL) 2015-11-03 US disclosed
US-20090275719-A1 Film Comprising Norbornene Compound Addition Polymer ZEON CORPORATION (JP) 2009-11-05 US disclosed
US-20090131488-A1 Compositions and methods for treating hyperproliferative epidermal diseases DERMIPSOR LTD. (IL) 2009-05-21 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed