SCHEMBL7528660

SCHEMBL7528660

[SiH3]O[SiH2]C1CC2C=CC1C2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5930917 0.78 KDM4E (0.31) KDM4ELMNA
SCHEMBL5442559 0.74
SCHEMBL5435943 0.74 KDM4E (0.32) KDM4E
SCHEMBL4454643 0.74 KDM4E (0.35) KDM4E
SCHEMBL4603756 0.74
SCHEMBL4603479 0.71 KDM4E (0.30) KDM4E
SCHEMBL9394579 0.70
SCHEMBL4603489 0.70
SCHEMBL4603485 0.69
SCHEMBL15483424 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002002721-A2 TOY BUBBLEMAKING SOLUTION HELIOGENESIS, INC. (US) 2002-01-10 WO disclosed
US-6252101-B1 ADDITION-CONDENSATION POLYMER WACKER-CHEMIE GMBH (DE) 2001-06-26 US disclosed
WO-1994021698-A1 NOVEL FUMARATE AND FUMARAMIDE SILOXANE HYDROGEL COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 1994-09-29 WO disclosed
WO-1992009644-A1 SURFACE MODIFICATION OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed