SCHEMBL445484

SCHEMBL445484

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nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 2/20 0.46
▸ ITGB1 P05556 2/20 0.35
▸ ITGA4 P13612 2/20 0.35
▸ ACE P12821 5/20 0.35
▸ DPP4 P27487 1/20 0.34
▸ NOS2 P35228 3/20 0.34
▸ NOS1 P29475 2/20 0.34
▸ NOS3 P29474 1/20 0.34
▸ SLC7A5 Q01650 1/20 0.33
▸ ECE1 P42892 1/20 0.33
▸ KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9326107 0.94 NOD1 (0.50) NOD1ITGB1ITGA4ACEDPP4
SCHEMBL2545708 0.87 NOD1 (0.48) NOD1ITGB1ITGA4ACEDPP4
SCHEMBL2545697 0.87 NOD1 (0.48) NOD1ITGB1ITGA4ACEDPP4
SCHEMBL30830405 0.87 NOD1 (0.48) NOD1ITGB1ITGA4ACEDPP4
SCHEMBL441159 0.87 NOD1 (0.45) NOD1DPP4
SCHEMBL10704006 0.81 NOD1 (0.44) NOD1ITGB1ITGA4ACEDPP4
SCHEMBL28610885 0.81 SLC7A5 (0.50) NOD1ITGB1ITGA4SLC7A5
SCHEMBL29430141 0.80 FNTA (0.37) NOD1ACE
SCHEMBL10621766 0.78 NOD1 (0.37) NOD1ITGB1ITGA4ACEKIF11
N-Monoacetylcystine SCHEMBL468824 0.78 MAPT (0.48) NOD1ITGB1ITGA4NOS2NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110418837-B Culture medium comprising oligopeptides 赢创运营有限公司 2024-04-02 — — CN disclosed
EP-3372671-B1 CULTURE MEDIUM COMPRISING OLGOPEPTIDES EVONIK OPERATIONS GMBH (DE) 2021-11-03 — — EP disclosed
EP-1144613-B2 METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES BOLDER BIOTECHNOLOGY INC (US) 2020-05-06 — — EP disclosed
WO-2018162346-A1 CULTURE MEDIUM COMPRISING OLIGOPEPTIDES EVONIK TECHNOCHEMIE GMBH (DE) 2018-09-13 — — WO disclosed
EP-3372671-A1 CULTURE MEDIUM COMPRISING OLGOPEPTIDES Evonik Technochemie GmbH (DE) 2018-09-12 — — EP disclosed
US-20170362626-A1 METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES BOLDER BIOTECHNOLOGY, INC. 2017-12-21 — — US disclosed
US-20160244798-A1 METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES BOLDER BIOTECHNOLOGY, INC. 2016-08-25 — — US disclosed
EP-2305804-B1 MonoPEGylated human growth hormone BOLDER BIOTECHNOLOGY INC (US) 2015-05-06 — — EP disclosed
US-8957023-B2 Methods for making proteins containing free cysteine residues BOLDER BIOTECHNOLOGY INC. (US) 2015-02-17 — — US disclosed
US-8932828-B2 Method for preparing recombinant granulocyte colony stimulating factor cysteine muteins BOLDER BIOTECHNOLOGY, INC. (US) 2015-01-13 — — US disclosed
WO-2001087925-A2 METHODS FOR REFOLDING PROTEINS CONTAINING FREE CYSTEINE RESIDUES BOLDER BIOTECHNOLOGY, INC. (US) 2001-11-22 — — WO disclosed
EP-1144613-A1 METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES Bolder Biotechnology, Inc. (US) 2001-10-17 — — EP disclosed
WO-2000042175-A1 METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES BOLDER BIOTECHNOLOGY INC. (US) 2000-07-20 — — WO disclosed
EP-0399656-B1 Nutrient compositions for amino acid supplementation in mammals KYOWA HAKKO KOGYO KK (JP) 1994-02-02 — — EP disclosed
US-5102871-A Admistering glutamy-cystine and or glutamyl-cysteine disulfide to a mammal to increase in vivo level of cysteine KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-04-07 — — US disclosed
EP-0264953-B1 USE OF N,N'-BIS-L-AMINO ACID-L-CYSTIN PEPTIDES IN AMINO ACID PREPARATIONS FOR ORAL AND PARENTERAL ADMINISTRATION PFRIMMER KABI GMBH & CO. KG (DE) 1991-05-08 — — EP disclosed
EP-0399656-A1 Nutrient compositions for amino acid supplementation in mammals KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1990-11-28 — — EP disclosed
US-4968696-A CHRONIC UREMIA OR HEPATIC CIRRHOSIS PFRIMMER + CO. PHARMAZEUTISCHE WERKE ERLANGEN GMBH + CO. KG (DE) 1990-11-06 — — US disclosed
WO-1988003150-A2 N,N'-BIS-AMINO ACID-L-CYSTINE-PEPTIDE-CONTAINING AMINO ACID PREPARATIONS FOR ORAL AND PARENTERAL ADMINISTRATION PFRIMMER + CO. PHARMAZEUTISCHE WERKE ERLANGEN GMBH (DE) 1988-05-05 — — WO disclosed
EP-0264953-A2 Use of N,N'-bis-L-amino acid-L-cystin peptides in amino acid preparations for oral and parenteral administration PFRIMMER KABI GMBH & CO. KG (DE) 1988-04-27 — — EP disclosed
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