Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264235 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL21581917 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL5309960 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL7522565 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL20604283 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL21581918 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL4537822 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL6357524 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL20604286 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 | |
| SCHEMBL1133209 | 1.00 | TSHR (0.67) | TSHRNAAADGKARAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273452-B2 | Polymeric films | ROHM AND HAAS COMPANY (US) | 2012-09-25 | — | — | US | disclosed |
| US-20090017287-A1 | Polymeric films | ROHM AND HAAS COMPANY | 2009-01-15 | — | — | US | disclosed |