Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470211 | 0.90 | LMNA (0.56) | MAPTKDM4EL3MBTL1NPSR1KDR | |
| SCHEMBL4462751 | 0.89 | MAPT (0.51) | MAPTKDM4EL3MBTL1NPSR1KDR | |
| SCHEMBL4457912 | 0.89 | LMNA (0.51) | MAPTKDM4EL3MBTL1NPSR1KDR | |
| SCHEMBL4459176 | 0.88 | LMNA (0.50) | MAPTKDM4EL3MBTL1NPSR1KDR | |
| SCHEMBL4460412 | 0.86 | MAPT (0.51) | MAPTKDM4EL3MBTL1NPSR1KDR | |
| SCHEMBL4461924 | 0.86 | MAPT (0.48) | MAPTKDM4EL3MBTL1NPSR1LMNA | |
| SCHEMBL4456454 | 0.85 | MAPT (0.50) | MAPTKDM4EL3MBTL1NPSR1LMNA | |
| SCHEMBL4468720 | 0.85 | LMNA (0.48) | MAPTKDM4EL3MBTL1NPSR1LMNA | |
| SCHEMBL4458673 | 0.85 | MAPT (0.51) | MAPTKDM4EL3MBTL1NPSR1LMNA | |
| SCHEMBL4461811 | 0.84 | MAPT (0.53) | MAPTKDM4EL3MBTL1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |