SCHEMBL44552

SCHEMBL44552

C=CC[Si]1(CC=C)CCCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15273454 0.98
SCHEMBL7167941 0.93
SCHEMBL18763582 0.88
SCHEMBL19466517 0.80
SCHEMBL9130033 0.80
SCHEMBL2588753 0.80 TSHR (0.31)
SCHEMBL8726270 0.78
SCHEMBL2640861 0.74
SCHEMBL10763524 0.74
SCHEMBL3772353 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3482236-B1 INCREASED STIFFNESS CENTER OPTIC IN SOFT CONTACT LENSES FOR ASTIGMATISM CORRECTION JOHNSON & JOHNSON VISION CARE (US) 2023-07-05 EP claimed
US-9528036-B2 Low-voc dialkyl-functional alkoxysiloxanes, processes and use thereof as hydrophobizing impregnating agents for mineral building materials EVONIK DEGUSSA GMBH (DE) 2016-12-27 US claimed
US-20160280810-A1 Method to Fabricate Polyolefin Polymer with Hydroxyl Functional Group LCY Chemical Corp. (TW) 2016-09-29 US claimed
CN-104974715-A Low VOC dialkyl-functional alkoxysiloxanes, method and their use as hydrophobizing impregnating agent for mineral building materials EVONIK INDUSTRIES AG 2015-10-14 CN claimed
US-20150284615-A1 LOW-VOC DIALKYL-FUNCTIONAL ALKOXYSILOXANES, PROCESSES AND USE THEREOF AS HYDROPHOBIZING IMPREGNATING AGENTS FOR MINERAL BUILDING MATERIALS EVONIK INDUSTRIES AG (DE) 2015-10-08 US claimed
US-20140235885-A1 COPOLYMERS OF EPOXY COMPOUNDS AND AMINO SILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-08-21 US claimed
WO-2013173119-A1 COPOLYMER OF EPOXY COMPOUNDS AND AMINO SILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-11-21 WO claimed
US-20130299390-A1 DEMULSIFYING COMPOSITIONS AND METHODS FOR SEPARATING EMULSIONS USING THE SAME MOMENTIVE PERFORMANCE MATERIALS INC. 2013-11-14 US claimed
EP-2589617-A2 Non-crosslinked reaction product of an epoxy or oxetane compound and an amino siloxane Momentive Performance Materials Inc. (US) 2013-05-08 EP claimed
US-20120220791-A1 COPOLYMERS OF EPOXY COMPOUNDS AND AMINO SILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-08-30 US claimed
US-20030088044-A1 Photocurable siloxane polymers ADVANCED MEDICAL OPTICS, INC. 2003-05-08 US claimed
US-6399734-B1 INJECTABLE LENS MATERIAL; MIXTURE OF SILOXANE COPOLYMER, PHOTOINITIATOR PHARMACIA AB (SE) 2002-06-04 US claimed
EP-1137955-A1 PHOTOCURABLE SILOXANE POLYMERS Pharmacia Groningen B.V. (NL) 2001-10-04 EP claimed
WO-2000022460-A1 PHOTOCURABLE SILOXANE POLYMERS PHARMACIA GRONINGEN BV (NL) 2000-04-20 WO claimed
US-5976703-A POLYSILPHENYLENESILOXANES FUJITSU LIMITED (JP) 1999-11-02 US claimed
US-5958806-A ANTISTATIC AGENT FIBERVISIONS A/S (DK) 1999-09-28 US claimed
EP-0378445-B1 Laminated packaging film MOBIL OIL CORP (US) 1998-05-27 EP claimed
EP-0687318-B1 CARDABLE HYDROPHOBIC POLYOLEFIN FIBRES DANAKLON AS (DK) 1996-12-27 EP claimed
EP-0496848-B1 MICROFIBERS OF RIGID POLYURETHANE HAVING LARGE AMOUNT OF HARD SEGMENT, NONWOVEN MATS OF THE MICROFIBERS AND MELT-BLOWING PROCESS FOR THE PRODUCTION THEREOF DOW CHEMICAL CO (US) 1996-02-21 EP claimed
EP-0378445-A2 Laminated packaging film MOBIL OIL CORPORATION (US) 1990-07-18 EP claimed