Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383626 | 0.85 | CA4 (0.40) | CA1CA4 | |
| SCHEMBL383628 | 0.85 | CA4 (0.40) | CA1CA4 | |
| Fumaric Acid SCHEMBL384838 | 0.79 | BBOX1 (0.36) | CA1 | |
| Acetic Acid SCHEMBL14940696 | 0.72 | CA1 (0.61) | CA1CA4LMNAALDH1A1TSHR | |
| Acetic Acid SCHEMBL153505 | 0.69 | CA1 (1.00) | CA1CA4LMNATSHR | |
| Acetic Acid SCHEMBL20830 | 0.69 | — | — | |
| Acetic Acid SCHEMBL103950 | 0.69 | — | — | |
| Acetic Acid SCHEMBL116885 | 0.69 | CA1 (0.89) | CA1CA4LMNAALDH1A1TSHR | |
| Acetic Acid SCHEMBL1254 | 0.69 | — | — | |
| Acetic Acid SCHEMBL272317 | 0.69 | CA1 (0.89) | CA1CA4LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456746-B1 | TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE | BRIDGESTONE CORP (JP) | 2023-04-19 | — | — | EP | disclosed |
| WO-2022124058-A1 | POLYMER-METAL COMPLEX, TIRE, AND POLYMER ARTICLE | 株式会社ブリヂストン | 2022-06-16 | — | — | WO | disclosed |
| EP-1958980-B1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR CORP (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20090270525-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| EP-1958980-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR Corporation (JP) | 2008-08-20 | — | — | EP | disclosed |
| EP-0175986-B1 | FILLER-CONTAINING SILICONE COMPOSITIONS | Dietrich, Heinz J., Dr. (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0175986-A1 | Filler-containing silicone compositions | Dietrich, Heinz J., Dr. (DE) | 1986-04-02 | — | — | EP | disclosed |