Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 11/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 5/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.48 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785663 | 1.00 | POLB (0.56) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL20828630 | 0.94 | POLB (0.57) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL7751294 | 0.92 | HTT (0.67) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL13478429 | 0.92 | TDP1 (0.48) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL9317039 | 0.89 | POLB (0.48) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL9317035 | 0.89 | POLB (0.48) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL20828629 | 0.89 | POLB (0.52) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL5332382 | 0.89 | TDP1 (0.52) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL5332386 | 0.89 | TDP1 (0.52) | POLBAPEX1HTTTDP1PPARA | |
| SCHEMBL18927175 | 0.87 | HTT (0.68) | POLBAPEX1HTTTDP1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1839076-B1 | YELLOW CHROMOPHORE AGENT COMPOSITION FOR INTRAOCULAR LENSES AND THE THUS OBTAINABLE LENSES | PHYSIOL (BE) | 2009-04-01 | — | — | EP | claimed |
| US-6001277-A | Liquid-crystal alignment film | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5543267-A | Photo-induced optically anisotropic amorphous film materials from side group polymers | AGFA-GEVAERT AG (DE) | 1996-08-06 | — | — | US | disclosed |