Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455487 | 1.00 | MEN1 (0.36) | MEN1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL4453948 | 0.81 | — | — | |
| SCHEMBL3934048 | 0.78 | MAPT (0.38) | MEN1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL3933193 | 0.77 | MAPT (0.37) | MEN1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL3934049 | 0.73 | MAPT (0.38) | MEN1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL3933201 | 0.73 | MAPT (0.37) | MEN1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL4453496 | 0.72 | CYP1A2 (0.46) | MEN1MAPTKMT2ALMNAMAPK1 | |
| Bromide SCHEMBL4456235 | 0.72 | MAPT (0.42) | MEN1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL3934652 | 0.70 | MAPT (0.37) | MEN1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL3934648 | 0.70 | MAPT (0.37) | MEN1MAPTKMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488353-B2 | Cationic heteroarylazine dyes and colorants containing these compounds | WELLA AG (DE) | 2009-02-10 | — | — | US | claimed |
| US-20070174975-A1 | Cationic heteroarylazine dyes and colorants containing these compounds | Wella GmbH (DE) | 2007-08-02 | — | — | US | claimed |
| US-7488353-B2 | Cationic heteroarylazine dyes and colorants containing these compounds | WELLA AG (DE) | 2009-02-10 | — | — | US | disclosed |
| US-20070174975-A1 | Cationic heteroarylazine dyes and colorants containing these compounds | Wella GmbH (DE) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070174975-A1 | Cationic heteroarylazine dyes and colorants containing these compounds | KRT18, IK, CRYZ | ACHE 2915/4885MEN1 4339/4885MAPT 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.