CRYZ

Quinone oxidoreductase · Q08257 · CRYZ on Sugi Atlas →

2,620 patent compounds predicted against CRYZ, 1,855 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL6691547	1.00	2/20
SCHEMBL6693404	1.00	2/20
SCHEMBL6691548	0.74	2/20
SCHEMBL6693720	0.71	2/20
SCHEMBL6690591	0.67	2/20
SCHEMBL6697964	0.65	2/20
SCHEMBL6693338	0.64	2/20
SCHEMBL6690595	0.62	2/20
SCHEMBL6695627	0.61	2/20
SCHEMBL6694531	0.60	2/20
SCHEMBL6692264	0.60	2/20
SCHEMBL6693341	0.56	2/20
SCHEMBL6694534	0.53	2/20
4-Hydroxycyclophosphamide (SCHEMBL406857)	0.51	2/20
4-Hydroxycyclophosphamide (SCHEMBL17737224)	0.51	2/20
Cyclophosphamide Anhydrous (SCHEMBL4346)	0.42	2/20
Cyclophosphamide Anhydrous (SCHEMBL7304)	0.42	2/20
Cyclophosphamide Anhydrous (SCHEMBL1285823)	0.42	2/20
Cyclophosphamide Anhydrous (SCHEMBL5328735)	0.42	2/20
Cyclophosphamide Anhydrous (SCHEMBL14192809)	0.42	2/20

Clinical trials — most relevant to CRYZ by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Physiological Intermolecular Modification Spectroscopy (PIMS) in Ulcerative Colitis With Golimumab	PHASE4	UNKNOWN
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision	PHASE3	COMPLETED
Comprehensive Study on Dry Eye and Ocular Surface Disease Prior and After Cataract Surgery	PHASE3	UNKNOWN
Safety and Dose-finding Study of DC-TAB in Healthy Subjects	PHASE1	COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors	PHASE1	COMPLETED
Cataract Surgery to Obtain Human Lens Material for the Study of Nuclear Cataracts	nan	COMPLETED
Studies of Families With Hereditary Cataracts	nan	COMPLETED
Proteomic Study of Tears From Patients With a PAX6 Mutation	nan	COMPLETED
Clinical and Genetic Studies of Families With Congenital or Hereditary Cataracts	nan	COMPLETED
Genetic Diagnosis in Congenital Cataracts	nan	COMPLETED
Heart Aging When Near Vision Difficulty Begins	nan	COMPLETED
PMCF Retrospective Study Outcomes of a Monofocal Toric Intraocular Lens	nan	COMPLETED
Vitreous Proteomics of Patients Suffering From Pseudoexfoliation Syndrome	nan	ACTIVE_NOT_RECRUITING
Alpha MSH in Ocular Disease	nan	COMPLETED
Gyrate Atrophy of the Choroid and Retina	nan	COMPLETED
Validation of Mesopic and Photopic Contrast Vision Tests With Respect to Nighttime Driving Ability	nan	COMPLETED
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults	nan	COMPLETED
Dynamic Light Scattering to Study Crystalline Proteins in Young Normal Lenses	nan	COMPLETED
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F	nan	ACTIVE_NOT_RECRUITING
Polarization Perception in Health and Disease. Testing a New Sight Test	nan	UNKNOWN
Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy (PRK)	nan	COMPLETED
Corneal Endothelium in Diabetics Undergoing Phacoemulsification	nan	UNKNOWN
MRB 0.3% Serum Effectiveness on 2 Early Clinical Markers of Photoinduced Cutaneous Aging: Actinic Lentigo and Actinic Keratosis	nan	UNKNOWN
Modified Surgical Techniques for Pediatric Cataract Treatment	nan	COMPLETED
The Molecular Pathogenesis Study of Cataract	nan	UNKNOWN
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma	nan	RECRUITING
Transcutaneous Electrical Diaphragmatic Stimulation in Critically Ill Elderly Patients	nan	UNKNOWN
Dynamic Light Scattering for Studying Lens Aging and Cataract Formation	nan	COMPLETED
Pilot Study: Dynamic Light Scattering Device for Studying Early Changes in Cataract	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a CRYZ binder may also engage these)

Protein	Name	Similarity
P11415	—	0.999	P11415 →
Q5R4S7	—	0.995	Q5R4S7 →
O97764	—	0.994	O97764 →
Q0MVN8	—	0.993	Q0MVN8 →
P47199	—	0.992	P47199 →
Q28452	—	0.991	Q28452 →
Q6AYT0	—	0.990	Q6AYT0 →
P48977	—	0.961	P48977 →
P12886	—	0.959	P12886 →
P14674	—	0.957	P14674 →
P14675	—	0.955	P14675 →
P14673	—	0.954	P14673 →
Q8LEB2	—	0.954	Q8LEB2 →
P25141	—	0.954	P25141 →
Q75ZX4	—	0.954	Q75ZX4 →
P17648	—	0.954	P17648 →
P13603	—	0.953	P13603 →
P06525	—	0.952	P06525 →
Q4R1E8	—	0.951	Q4R1E8 →
P00333	—	0.951	P00333 →
Q0ITW7	—	0.950	Q0ITW7 →
P14219	—	0.950	P14219 →
P28032	—	0.950	P28032 →
Q2R8Z5	—	0.949	Q2R8Z5 →
P10848	—	0.948	P10848 →
O23939	—	0.948	O23939 →
P04707	—	0.947	P04707 →
P05336	—	0.946	P05336 →
Q58D31	—	0.944	Q58D31 →
Q941I0	—	0.943	Q941I0 →