Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 7/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468908 | 0.82 | NPC1 (0.39) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4457420 | 0.73 | NPC1 (0.50) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4464697 | 0.73 | NPC1 (0.50) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4456761 | 0.72 | NPC1 (0.49) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4456756 | 0.72 | NPC1 (0.49) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL7682517 | 0.71 | NPC1 (0.51) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL7682513 | 0.71 | NPC1 (0.51) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4464835 | 0.71 | NPC1 (0.49) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4468163 | 0.71 | NPC1 (0.49) | RAB9ANPC1GAASCDSMN1; SMN2 | |
| SCHEMBL4452899 | 0.71 | NPC1 (0.45) | RAB9ANPC1GAASCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |