Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 7/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457420 | 1.00 | NPC1 (0.50) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4456756 | 0.99 | NPC1 (0.49) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4456761 | 0.99 | NPC1 (0.49) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| SCHEMBL4468163 | 0.89 | NPC1 (0.49) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| SCHEMBL4464835 | 0.89 | NPC1 (0.49) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| SCHEMBL7682517 | 0.87 | NPC1 (0.51) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| SCHEMBL7682513 | 0.87 | NPC1 (0.51) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| SCHEMBL4464723 | 0.86 | NPC1 (0.52) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| SCHEMBL13408963 | 0.85 | CTSS (0.46) | NPC1RAB9AGAASCDSMN1; SMN2 | |
| SCHEMBL14195628 | 0.85 | CTSS (0.46) | NPC1RAB9AGAASCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| US-20100105685-A1 | S-Nitrosothiol Compounds and Related Derivatives | GALLEON PHARMACEUTICALS, INC. | 2010-04-29 | — | — | US | disclosed |
| US-20100105685-A1 | S-Nitrosothiol Compounds and Related Derivatives | GALLEON PHARMACEUTICALS, INC. | 2010-04-29 | — | — | US | disclosed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105685-A1 | S-Nitrosothiol Compounds and Related Derivatives | NNMT, BHMT2, SQOR | NPC1 1037/4885RAB9A 4159/4885GAA 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.