SCHEMBL4455629

SCHEMBL4455629

CCCC(CCCC(CC)(c1ccc(O)cc1)c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.78

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 17/20 0.78
ESR2 Q92731 10/20 0.78
AR P10275 1/20 0.50
SHBG P04278 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1334149 0.92 ESR1 (0.83) ESR1ESR2ARSHBG
SCHEMBL6562079 0.89 ESR1 (0.85) ESR1ESR2ARSHBG
SCHEMBL6561244 0.89 ESR1 (0.92) ESR1ESR2AR
SCHEMBL272801 0.88 ESR1 (1.00) ESR1ESR2AR
SCHEMBL6561210 0.87 ESR1 (0.75) ESR1ESR2ARSHBG
SCHEMBL11185741 0.87 ESR1 (0.81) ESR1ESR2ARSHBG
SCHEMBL15987572 0.85 ESR1 (0.72) ESR1ESR2SHBG
SCHEMBL11182155 0.85 ESR1 (0.79) ESR1ESR2ARSHBG
SCHEMBL9396698 0.85 ESR1 (0.79) ESR1ESR2ARSHBG
SCHEMBL28255062 0.85 ESR1 (0.79) ESR1ESR2ARSHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
EP-0031958-A2 Fire retardant polycarbonates with improved critical thickness and process for their preparation Mobay Chemical Corporation (US) 1981-07-15 EP disclosed