SCHEMBL4455749

SCHEMBL4455749

CCCCCCCCc1cc2c(cc1O)C1(CC2(C)C)CC(C)(C)c2cc(CCCCCCCC)c(O)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.46
TYR P14679 3/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
KMT2A Q03164 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CNR2 P34972 2/20 0.37
PTGS2 P35354 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4464622 1.00 ALOX5 (0.46) ALOX5TYRMEN1MAPTHTT
SCHEMBL4472385 1.00 ALOX5 (0.46) ALOX5TYRMEN1MAPTHTT
SCHEMBL4460492 1.00 ALOX5 (0.46) ALOX5TYRMEN1MAPTHTT
SCHEMBL4459384 1.00 ALOX5 (0.46) ALOX5TYRMEN1MAPTHTT
SCHEMBL4457783 1.00 ALOX5 (0.46) ALOX5TYRMEN1MAPTHTT
SCHEMBL4464463 1.00 ALOX5 (0.46) ALOX5TYRMEN1MAPTHTT
SCHEMBL4460617 0.98 ALOX5 (0.44) ALOX5TYRMEN1MAPTHTT
SCHEMBL4462294 0.94 TYR (0.44) ALOX5TYRMEN1MAPTHTT
SCHEMBL4460121 0.90 CNR2 (0.38) ALOX5TYRMEN1MAPTHTT
SCHEMBL4460505 0.88 HMGCR (0.42) ALOX5TYRMEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed