Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35098 | 0.98 | TSHR (0.60) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL27599930 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL20395035 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28247072 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28407341 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL25211249 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28173664 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL440630 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL5969204 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| Benzene SCHEMBL27982505 | 0.95 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065179-A1 | PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | YKI, Ytemiska Institutet AB (SE) | 2012-03-15 | — | — | US | disclosed |
| EP-2419398-A1 | A PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | YKI, Ytkemiska Institutet AB (SE) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010120232-A1 | A PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | YKI, YTKEMISKA INSTITUTET AB (SE) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065179-A1 | PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | BCKDK, KHK, CA7 | TSHR 3804/4885LMNA 1615/4885F2 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.