SCHEMBL4455847

SCHEMBL4455847

CCCCC(CCS)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.65
MAPK1 P28482 1/20 0.65
FOLH1 Q04609 4/20 0.57
CHRM1 P11229 1/20 0.56
AKR1A1 P14550 1/20 0.56
CHRM3 P20309 1/20 0.56
HTR2A P28223 1/20 0.56
HTR2C P28335 1/20 0.56
ADRA1A P35348 1/20 0.56
HRH1 P35367 1/20 0.56
DRD3 P35462 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC2 Q92769 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
SLC1A2 P43004 2/20 0.55
SLC1A1 P43005 2/20 0.55
SLC1A3 P43003 1/20 0.55
GRIK1 P39086 2/20 0.48
GRIK2 Q13002 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11295428 0.92 GRIK1 (0.58) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL11288996 0.92 GRIK1 (0.58) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL9777682 0.92 GRIK1 (0.58) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL11598279 0.92 GRIK1 (0.58) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL11704362 0.92 GRIK1 (0.58) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL4455550 0.92 GRIK1 (0.58) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL4454959 0.92 GRIK1 (0.58) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL5829349 0.89 FOLH1 (0.66) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL593706 0.89 CA2 (0.81) CA2MAPK1FOLH1CHRM1AKR1A1
SCHEMBL18640749 0.88 FOLH1 (0.67) CA2MAPK1FOLH1CHRM1AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7488433-B2 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM AND HAAS COMPANY (US) 2009-02-10 US disclosed
EP-1342749-B1 Organic based thermal stabilizers and heat stabilized polymer compositions ROHM & HAAS (US) 2007-11-21 EP disclosed
EP-1621576-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2007-02-14 EP disclosed
US-7112622-B2 Organic based thermal stabilizers and heat stabilized polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-26 US disclosed
US-7109261-B2 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-19 US disclosed
US-7105109-B2 Latent mercaptans as stabilizers for halogen-containing polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-12 US disclosed
EP-1318169-B1 Stabilized halogen-containing polymer composition ROHM & HAAS (US) 2006-06-14 EP disclosed
US-7025904-B2 Method for improving adhesion of water-based inks to halogen-containing resin articles ROHM AND HAAS COMPANY (US) 2006-04-11 US disclosed
US-20060025503-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers PMC CINCINNATI, INC. 2006-02-02 US disclosed
EP-1621576-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-02-01 EP disclosed
WO-2003014244-A1 BINDING AGENT COMPONENT FOR SURFACE COATING AGENTS WITH IMPROVED ADHESIVE PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-02-20 WO disclosed
US-20020091179-A1 Halogen-containing polymer composition stabilized by a latent mercaptan and a mixture of a zinc carboxylate and zinc chloride NORRIS GENE KELLY (US) 2002-07-11 US disclosed
US-20020086920-A1 METHOD FOR IMPROVING ADHENSION OF WATER-BASED INKS TO HALOGEN- CONTAINING RESIN ARTICLES PMC CINCINNATI, INC. 2002-07-04 US disclosed
US-20020068780-A1 LATENT MERCAPTANS AS MULTI-FUNCTIONAL ADDITIVES FOR HALOGEN-CONTAINING POLYMER COMPOSITIONS PMC CINCINNATI, INC. 2002-06-06 US disclosed
EP-1201706-A1 A halogen-containing polymer composition stabilized by a latent mercaptan and a mixture of a zinc carboxylate and zinc chloride ROHM AND HAAS COMPANY (US) 2002-05-02 EP disclosed
US-6326518-B1 HEAT STABILIZER MORTON INTERNATIONAL, INC. 2001-12-04 US disclosed
US-6232380-B1 HEAT RESISTANCE, PHOTOSTABILITY, WEATHERPROOFING MORTON INTERNATIONAL INC. 2001-05-15 US disclosed
EP-1055704-A2 Method for improving adhesion of water based inks to halogen containing resin articles ROHM AND HAAS COMPANY (US) 2000-11-29 EP disclosed
EP-1004624-A1 Latent mercaptan stabilizers for improved weatherability of clear halogen-containing polymer compositions MORTON INTERNATIONAL, INC. (US) 2000-05-31 EP disclosed
US-4391757-A Organic antimony containing stabilizer compositions for halogenated polymers CARSTAB CORPORATION (US) 1983-07-05 US disclosed