SCHEMBL4456017

SCHEMBL4456017

CCCOP(=O)(C=O)OCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP3A4 P08684 2/20 0.39
LPAR3 Q9UBY5 5/20 0.33
LPAR1 Q92633 3/20 0.33
LPAR2 Q9HBW0 3/20 0.33
TSHR P16473 3/20 0.33
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ADH1B P00325 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31
S1PR2 O95136 4/20 0.30
S1PR4 O95977 4/20 0.30
S1PR1 P21453 4/20 0.30
S1PR3 Q99500 4/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4612062 0.85 CTSA (0.32) MEN1KMT2ACYP3A4
SCHEMBL4450985 0.85 CYP3A4 (0.58) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL28089281 0.83 LPAR3 (0.54) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL9081845 0.79 MEN1 (0.39) MEN1KMT2ACYP3A4LPAR3LPAR1
SCHEMBL1396448 0.78 TSHR (0.50) TSHRTP53TDP1CA12CA1
SCHEMBL779610 0.77 MEN1 (0.38) MEN1KMT2ACYP3A4LPAR3LPAR1
SCHEMBL5357461 0.76 TSHR (0.48) TSHRTP53TDP1CA12CA1
SCHEMBL4813823 0.75 MEN1 (0.36) MEN1KMT2ACYP3A4LPAR3LPAR1
SCHEMBL4813841 0.75 MEN1 (0.36) MEN1KMT2ACYP3A4LPAR3LPAR1
Benzene SCHEMBL25317681 0.72 NPSR1 (0.47) MEN1KMT2ATSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed