SCHEMBL4612062

SCHEMBL4612062

CC(C)OP(=O)(C=O)OC(C)C.CCCOP(=O)(C=O)OCCC

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.32
ACHE P22303 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4456017 0.85 MEN1 (0.39) MEN1KMT2ACYP3A4
SCHEMBL27891368 0.81 CTSA (0.46) CTSAACHE
SCHEMBL29187644 0.73 CYP3A4 (0.46) CTSAACHEMEN1KMT2ACYP3A4
SCHEMBL3823577 0.73 CYP3A4 (0.46) CTSAACHEMEN1KMT2ACYP3A4
SCHEMBL4450985 0.73 CYP3A4 (0.58) CYP3A4
SCHEMBL28089281 0.71 LPAR3 (0.54) CYP3A4
SCHEMBL9938963 0.69 CTSA (0.58) CTSAACHEMEN1KMT2ACYP3A4
SCHEMBL12563529 0.69 LPAR3 (0.38) CTSAACHEMEN1KMT2A
SCHEMBL28848586 0.68 CYP3A4 (0.41) CTSAACHEMEN1KMT2ACYP3A4
SCHEMBL28390976 0.68 CTSA (0.34) CTSAACHEMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1419182-B1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORP (JP) 2008-10-15 EP disclosed
EP-1419182-A1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6610804-B2 An iron compound, an alpha-acylphosphonate diester, and an organoaluminum compound BRIDGESTONE CORPORATION (JP) 2003-08-26 US disclosed
US-6576725-B1 Iron compound, organomagnesium compound, and alpha-acylphosphonate diester; addition polymerization BRIDGESTONE CORPORATION (JP) 2003-06-10 US disclosed
US-20030073790-A1 Iron-based catalyst composition for the manufacture of syndiotactic 1, 2-polybutadiene BRIDGESTONE CORP. 2003-04-17 US disclosed
US-20030073570-A1 Method of preparing oligomers of conjugated dienes with an iron-based catalyst composition BRIDGESTONE CORP. 2003-04-17 US disclosed
WO-2003018644-A1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2003-03-06 WO disclosed