Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837606 | 1.00 | NR3C1 (0.59) | NR3C1PGR | |
| SCHEMBL834494 | 0.92 | NR3C1 (0.63) | NR3C1PGR | |
| SCHEMBL834495 | 0.92 | NR3C1 (0.63) | NR3C1PGR | |
| SCHEMBL836480 | 0.89 | NR3C1 (0.60) | NR3C1PGR | |
| SCHEMBL13208636 | 0.89 | NR3C1 (0.60) | NR3C1PGR | |
| SCHEMBL3824927 | 0.89 | NR3C1 (0.60) | NR3C1PGR | |
| SCHEMBL851033 | 0.89 | NR3C1 (0.60) | NR3C1PGR | |
| SCHEMBL835609 | 0.87 | NR3C1 (0.61) | NR3C1PGR | |
| SCHEMBL835608 | 0.87 | NR3C1 (0.61) | NR3C1PGR | |
| SCHEMBL836255 | 0.87 | NR3C1 (0.61) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102169-A1 | INDAZOLYL ESTER AND AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | AstraZeneca AB (SE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008076048-A1 | INDAZOLYL ESTER AND AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |