Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.45 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456059 | 1.00 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4452740 | 0.89 | MAPT (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4452736 | 0.89 | MAPT (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13783790 | 0.83 | CNR1 (0.41) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4457335 | 0.83 | CNR1 (0.41) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4457337 | 0.83 | CNR1 (0.41) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13783917 | 0.81 | CNR1 (0.41) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL4458275 | 0.81 | CCR3 (0.47) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13783977 | 0.81 | CCR3 (0.47) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4458269 | 0.81 | CCR3 (0.47) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |