SCHEMBL4456360

SCHEMBL4456360

C=C(C)COC(=O)/C=C\C(=O)OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.54
KEAP1 Q14145 1/20 0.54
NFE2L2 Q16236 1/20 0.54
MAPT P10636 7/20 0.38
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ATM Q13315 1/20 0.38
GFPT1 Q06210 1/20 0.36
ALOX15 P16050 1/20 0.35
RECQL P46063 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
LMNA P02545 2/20 0.35
THRB P10828 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
MDM4 O15151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4456361 1.00 HCAR2 (0.54) HCAR2KEAP1NFE2L2MAPTALDH1A1
SCHEMBL10688847 0.91 HCAR2 (0.43) HCAR2KEAP1NFE2L2MAPTALDH1A1
SCHEMBL868205 0.91 HCAR2 (0.43) HCAR2KEAP1NFE2L2MAPTALDH1A1
SCHEMBL10688851 0.83 HCAR2 (0.57) HCAR2MAPTALDH1A1KDM4ETDP1
SCHEMBL868207 0.83 HCAR2 (0.57) HCAR2MAPTALDH1A1KDM4ETDP1
SCHEMBL868206 0.83 HCAR2 (0.57) HCAR2MAPTALDH1A1KDM4ETDP1
SCHEMBL30475127 0.83 HCAR2 (0.57) HCAR2MAPTALDH1A1ATMHSD17B10
SCHEMBL2627702 0.83 HCAR2 (0.59) HCAR2KEAP1NFE2L2MAPTALDH1A1
SCHEMBL17048352 0.80 HCAR2 (0.62) HCAR2KEAP1NFE2L2MAPTALDH1A1
SCHEMBL17048353 0.80 HCAR2 (0.62) HCAR2KEAP1NFE2L2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090030160-A1 Polylactic Acid Complex and Production Method Thereof SUMITOMO ELECTRIC FINE POLYMER INC. (JP) 2009-01-29 US disclosed
US-20080213209-A1 Process for Producing Cross-Linked Material of Polylactic Acid and Cross-Linked Material of Polylactic Acid SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2008-09-04 US disclosed
US-20050242466-A1 Process for producing transparent material made of polylactic acid and transparent material made of polylactic acid SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2005-11-03 US disclosed